L2HGDH Full-Length MS Protein Standard


Product Description:

Name L2HGDH Full-Length MS Protein Standard
Cat# CPFL317631
Protein NameL-2-hydroxyglutarate dehydrogenase
SymbolL2HGDH
SynonymsC14orf160; L2HGA
AccessionNM_024884
Cytogenetic14q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW45.2 kDa
Expression TrueORF CloneRC217631
DescriptionL2HGDH Full-Length MS Protein Standard (NP_079160), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

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