GEMIN5 Full-Length MS Protein Standard


Product Description:

Name GEMIN5 Full-Length MS Protein Standard
Cat# CPFL317516
Protein Namegem (nuclear organelle) associated protein 5
SymbolGEMIN5
SynonymsGEMIN-5
AccessionNM_015465
Cytogenetic5q33.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW168.4 kDa
Expression TrueORF CloneRC217516
DescriptionGEMIN5 Full-Length MS Protein Standard (NP_056280), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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