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ITGAE Full-Length MS Protein Standard

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Product Description


NameITGAE Full-Length MS Protein Standard
Cat#CPFL317265
Protein Nameintegrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
SymbolITGAE
SynonymsCD103; HUMINAE
AccessionNM_002208
Cytogenetic17p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionITGAE Full-Length MS Protein Standard (NP_002199), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

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