DCTD Full-Length MS Protein Standard


Product Description:

Name DCTD Full-Length MS Protein Standard
Cat# CPFL317231
Protein NamedCMP deaminase
SymbolDCTD
SynonymsMGC111062
AccessionNM_001921
Cytogenetic4q35.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW19.8 kDa
Expression TrueORF CloneRC217231
DescriptionDCTD Full-Length MS Protein Standard (NP_001912), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.

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