BDNF Full-Length MS Protein Standard


Product Description:

Name BDNF Full-Length MS Protein Standard
Cat# CPFL317124
Protein Namebrain-derived neurotrophic factor
SymbolBDNF
SynonymsANON2; BULN2
AccessionNM_170734
Cytogenetic11p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW25.7 kDa
Expression TrueORF CloneRC217124
DescriptionBDNF Full-Length MS Protein Standard (NP_733930), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimers and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.

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