DYNC1I1 Full-Length MS Protein Standard


Product Description:

Name DYNC1I1 Full-Length MS Protein Standard
Cat# CPFL317108
Protein Namedynein, cytoplasmic 1, intermediate chain 1
SymbolDYNC1I1
SynonymsDNCI1; DNCIC1
AccessionNM_004411
Cytogenetic7q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW72.8 kDa
Expression TrueORF CloneRC217108
DescriptionDYNC1I1 Full-Length MS Protein Standard (NP_004402), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

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