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GYPC Full-Length MS Protein Standard

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Product Description


NameGYPC Full-Length MS Protein Standard
Cat#CPFL317103
Protein Nameglycophorin C (Gerbich blood group)
SymbolGYPC
SynonymsCD236; CD236R; GE; GPC; GPD; GYPD; PAS-2; PAS-2
AccessionNM_016815
Cytogenetic2q14-q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGYPC Full-Length MS Protein Standard (NP_058131), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.

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