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MET Full-Length MS Protein Standard

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Product Description


NameMET Full-Length MS Protein Standard
Cat#CPFL317003
Protein Namemet proto-oncogene
SymbolMET
SynonymsAUTS9; c-Met; HGFR; RCCP2
AccessionNM_000245
Cytogenetic7q31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMET Full-Length MS Protein Standard (NP_000236), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

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