USP8 Full-Length MS Protein Standard


Product Description:

Name USP8 Full-Length MS Protein Standard
Cat# CPFL316926
Protein Nameubiquitin specific peptidase 8
SymbolUSP8
SynonymsHumORF8; SPG59; UBPY
AccessionNM_005154
Cytogenetic15q21.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW127.3 kDa
Expression TrueORF CloneRC216926
DescriptionUSP8 Full-Length MS Protein Standard (NP_005145), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.

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