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HAO1 Full-Length MS Protein Standard

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Product Description


NameHAO1 Full-Length MS Protein Standard
Cat#CPFL316834
Protein Namehydroxyacid oxidase (glycolate oxidase) 1
SymbolHAO1
SynonymsGOX; GOX1; HAOX1
AccessionNM_017545
Cytogenetic20p12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHAO1 Full-Length MS Protein Standard (NP_060015), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.

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