SEC31A Full-Length MS Protein Standard


Product Description:

Name SEC31A Full-Length MS Protein Standard
Cat# CPFL316802
Protein NameSEC31 homolog A
SymbolSEC31A
SynonymsABP125; ABP130; HSPC275; HSPC334; SEC31L1
AccessionNM_001077208
Cytogenetic4q21.22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW131.4 kDa
Expression TrueORF CloneRC216802
DescriptionSEC31A Full-Length MS Protein Standard (NP_001070676), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.

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