Home > Products > Stable Isotope Labeled Full Length MS Protein Standard > IL10 Full-Length MS Protein Standard

IL10 Full-Length MS Protein Standard


Product Description

NameIL10 Full-Length MS Protein Standard
Protein Nameinterleukin 10
SynonymsCSIF; GVHDS; IL-10; IL10A; TGIF
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIL10 Full-Length MS Protein Standard (NP_000563), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Products List:

Cat#Protein SequencePrice

If the product of interest is not available in our catalog, we can synthesize for you with our quality controlled
Customized Synthesized Peptide/Proteins Service!

Online Inquiry

Please input "proteomics" as verification code.