LRPPRC Full-Length MS Protein Standard


Product Description:

Name LRPPRC Full-Length MS Protein Standard
Cat# CPFL316747
Protein Nameleucine-rich pentatricopeptide repeat containing
SymbolLRPPRC
SynonymsCLONE-23970; GP130; LRP130; LSFC
AccessionNM_133259
Cytogenetic2p21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW157.7 kDa
Expression TrueORF CloneRC216747
DescriptionLRPPRC Full-Length MS Protein Standard (NP_573566), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.

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