INF2 Full-Length MS Protein Standard


Product Description:

Name INF2 Full-Length MS Protein Standard
Cat# CPFL316716
Protein Nameinverted formin, FH2 and WH2 domain containing
SymbolINF2
SynonymsC14orf151; C14orf173; CMTDIE; FSGS5; pp9484
AccessionNM_022489
Cytogenetic14q32.33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW135.4 kDa
Expression TrueORF CloneRC216716
DescriptionINF2 Full-Length MS Protein Standard (NP_071934), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.

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