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BPNT1 Full-Length MS Protein Standard

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Product Description


NameBPNT1 Full-Length MS Protein Standard
Cat#CPFL316622
Protein Name3(2), 5-bisphosphate nucleotidase 1
SymbolBPNT1
SynonymsHEL20; PIP
AccessionNM_006085
Cytogenetic1q41
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionBPNT1 Full-Length MS Protein Standard (NP_006076), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntases physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

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