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GABRA5 Full-Length MS Protein Standard

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Product Description


NameGABRA5 Full-Length MS Protein Standard
Cat#CPFL316541
Protein Namegamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
SymbolGABRA5
SynonymsMGC138184
AccessionNM_000810
Cytogenetic15q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGABRA5 Full-Length MS Protein Standard (NP_000801), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.

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