GRIN1 Full-Length MS Protein Standard


Product Description:

Name GRIN1 Full-Length MS Protein Standard
Cat# CPFL316458
Protein Nameglutamate receptor, ionotropic, N-methyl D-aspartate 1
SymbolGRIN1
SynonymsGluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1
AccessionNM_007327
Cytogenetic9q34.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW103.4 kDa
Expression TrueORF CloneRC216458
DescriptionGRIN1 Full-Length MS Protein Standard (NP_015566), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.

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