CYP26A1 Full-Length MS Protein Standard


Product Description:

Name CYP26A1 Full-Length MS Protein Standard
Cat# CPFL316278
Protein Namecytochrome P450, family 26, subfamily A, polypeptide 1
SymbolCYP26A1
SynonymsCP26; CYP26; P450RAI; P450RAI1
AccessionNM_000783
Cytogenetic10q23-q24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW56 kDa
Expression TrueORF CloneRC216278
DescriptionCYP26A1 Full-Length MS Protein Standard (NP_000774), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported.

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