PDE6G Full-Length MS Protein Standard


Product Description:

Name PDE6G Full-Length MS Protein Standard
Cat# CPFL316236
Protein Namephosphodiesterase 6G, cGMP-specific, rod, gamma
SymbolPDE6G
SynonymsPDEG; RP57
AccessionNM_002602
Cytogenetic17q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW9.5 kDa
Expression TrueORF CloneRC216236
DescriptionPDE6G Full-Length MS Protein Standard (NP_002593), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.

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