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GRB14 Full-Length MS Protein Standard

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Product Description


NameGRB14 Full-Length MS Protein Standard
Cat#CPFL316110
Protein Namegrowth factor receptor-bound protein 14
SymbolGRB14
Synonymsgrowth factor receptor-bound protein 14
AccessionNM_004490
Cytogenetic2q22-q24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGRB14 Full-Length MS Protein Standard (NP_004481), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date.

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