COL15A1 Full-Length MS Protein Standard


Product Description:

Name COL15A1 Full-Length MS Protein Standard
Cat# CPFL315981
Protein Namecollagen, type XV, alpha 1
SymbolCOL15A1
SynonymsFLJ38566
AccessionNM_001855
Cytogenetic9q21-q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW138.9 kDa
Expression TrueORF CloneRC215981
DescriptionCOL15A1 Full-Length MS Protein Standard (NP_001846), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.

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