BHLHA15 Full-Length MS Protein Standard


Product Description:

Name BHLHA15 Full-Length MS Protein Standard
Cat# CPFL315938
Protein Namebasic helix-loop-helix family, member a15
SymbolBHLHA15
SynonymsBHLHB8; MIST1
AccessionNM_177455
Cytogenetic7q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW20.6 kDa
Expression TrueORF CloneRC215938
DescriptionBHLHA15 Full-Length MS Protein Standard (NP_803238), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5-CANNTG-3.

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