FTO Full-Length MS Protein Standard


Product Description:

Name FTO Full-Length MS Protein Standard
Cat# CPFL315889
Protein Namefat mass and obesity associated
SymbolFTO
SynonymsALKBH9
AccessionNM_001080432
Cytogenetic16q12.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW58.1 kDa
Expression TrueORF CloneRC215889
DescriptionFTO Full-Length MS Protein Standard (NP_001073901), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

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