HYAL1 Full-Length MS Protein Standard


Product Description:

Name HYAL1 Full-Length MS Protein Standard
Cat# CPFL315525
Protein Namehyaluronoglucosaminidase 1
SymbolHYAL1
SynonymsHYAL-1; LUCA1; MGC45987; NAT6
AccessionNM_007312
Cytogenetic3p21.31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW48.2 kDa
Expression TrueORF CloneRC215525
DescriptionHYAL1 Full-Length MS Protein Standard (NP_009296), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

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