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NVL Full-Length MS Protein Standard

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Product Description


NameNVL Full-Length MS Protein Standard
Cat#CPFL315387
Protein Namenuclear VCP-like
SymbolNVL
Synonymsnuclear VCP-like; nuclear VCP-like protein; Nuclear valosin-containing protein-like; OTTHUMP00000035641
AccessionNM_002533
Cytogenetic1q41-q42.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNVL Full-Length MS Protein Standard (NP_002524), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.

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