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HDAC7 Full-Length MS Protein Standard

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Product Description


NameHDAC7 Full-Length MS Protein Standard
Cat#CPFL315233
Protein Namehistone deacetylase 7
SymbolHDAC7
SynonymsHD7A; HDAC7A
AccessionNM_015401
Cytogenetic12q13.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHDAC7 Full-Length MS Protein Standard (NP_056216), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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