ACCN4 Full-Length MS Protein Standard


Product Description:

Name ACCN4 Full-Length MS Protein Standard
Cat# CPFL315051
Protein Nameamiloride-sensitive cation channel 4, pituitary
SymbolACCN4
SynonymsASIC4; BNAC4; MGC17248; MGC24860
AccessionNM_018674
Cytogenetic2q35
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW72 kDa
Expression TrueORF CloneRC215051
DescriptionACCN4 Full-Length MS Protein Standard (NP_061144), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.

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