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ROR1 Full-Length MS Protein Standard

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Product Description


NameROR1 Full-Length MS Protein Standard
Cat#CPFL314967
Protein Namereceptor tyrosine kinase-like orphan receptor 1
SymbolROR1
SynonymsdJ537F10.1; NTRKR1
AccessionNM_005012
Cytogenetic1p32-p31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionROR1 Full-Length MS Protein Standard (NP_005003), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

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