UHMK1 Full-Length MS Protein Standard


Product Description:

Name UHMK1 Full-Length MS Protein Standard
Cat# CPFL314962
Protein NameU2AF homology motif (UHM) kinase 1
SymbolUHMK1
SynonymsKIS; KIST; P-CIP2
AccessionNM_175866
Cytogenetic1q23.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW46.4 kDa
Expression TrueORF CloneRC214962
DescriptionUHMK1 Full-Length MS Protein Standard (NP_787062), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The gene encodes a serine/threonine protein kinase that promotes cell cycle progression through G1 by phosphorylation of the cyclin-dependent kinase inhibitor 1B (p27Kip1), which causes nuclear export and degradation. The encoded protein is also thought to function in the adult nervous system and the gene has been associated with schizophrenia. Alternative splicing results in multiple transcript variants.

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