EGFR Full-Length MS Protein Standard


Product Description:

Name EGFR Full-Length MS Protein Standard
Cat# CPFL314877
Protein Nameepidermal growth factor receptor
SymbolEGFR
SynonymsERBB; ERBB1; HER1; mENA; NISBD2; PIG61
AccessionNM_201283
Cytogenetic7p12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW42.4 kDa
Expression TrueORF CloneRC214877
DescriptionEGFR Full-Length MS Protein Standard (NP_958440), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

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