|Name||GSN Full-Length MS Protein Standard|
|Amino Acid Labeled||[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys|
|Chemical Purity||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Expression Host||Human HEK293 cells|
|Predicted MW||82.9 kDa|
|Expression TrueORF Clone||RC214871|
|Description||GSN Full-Length MS Protein Standard (NP_000168), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene binds to the plus ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.|
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