| Name | GSN Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL314871 |
| Protein Name | gelsolin |
| Symbol | GSN |
| Synonyms | ADF; AGEL |
| Accession | NM_000177 |
| Cytogenetic | 9q33 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 82.9 kDa |
| Expression TrueORF Clone | RC214871 |
| Description | GSN Full-Length MS Protein Standard (NP_000168), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene binds to the plus ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. |
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