MAML1 Full-Length MS Protein Standard


Product Description:

Name MAML1 Full-Length MS Protein Standard
Cat# CPFL314790
Protein Namemastermind-like 1 (Drosophila)
SymbolMAML1
SynonymsMam-1; Mam1
AccessionNM_014757
Cytogenetic5q35
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW107.9 kDa
Expression TrueORF CloneRC214790
DescriptionMAML1 Full-Length MS Protein Standard (NP_055572), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

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