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CLN5 Full-Length MS Protein Standard

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Product Description


NameCLN5 Full-Length MS Protein Standard
Cat#CPFL314709
Protein Nameceroid-lipofuscinosis, neuronal 5
SymbolCLN5
SynonymsNCL
AccessionNM_006493
Cytogenetic13q21.1-q32
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCLN5 Full-Length MS Protein Standard (NP_006484), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

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