HMGA2 Full-Length MS Protein Standard


Product Description:

Name HMGA2 Full-Length MS Protein Standard
Cat# CPFL314681
Protein Namehigh mobility group AT-hook 2
SymbolHMGA2
SynonymsBABL; HMGI-C; HMGIC; LIPO; STQTL9
AccessionNM_003484
Cytogenetic12q15
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW11.3 kDa
Expression TrueORF CloneRC214681
DescriptionHMGA2 Full-Length MS Protein Standard (NP_003475), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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