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DAB1 Full-Length MS Protein Standard

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Product Description


NameDAB1 Full-Length MS Protein Standard
Cat#CPFL314664
Protein Namedisabled homolog 1
SymbolDAB1
SynonymsOTTHUMP00000010045; OTTHUMP00000011753; disabled homolog 1; disabled homolog 1 (Drosophila)
AccessionNM_021080
Cytogenetic1p32-p31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDAB1 Full-Length MS Protein Standard (NP_066566), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

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