CCT4 Full-Length MS Protein Standard


Product Description:

Name CCT4 Full-Length MS Protein Standard
Cat# CPFL314480
Protein Namechaperonin containing TCP1, subunit 4 (delta)
SymbolCCT4
SynonymsCCT-DELTA; Cctd; SRB
AccessionNM_006430
Cytogenetic2p15
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW57.7 kDa
Expression TrueORF CloneRC214480
DescriptionCCT4 Full-Length MS Protein Standard (NP_006421), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 )

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