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GCKR Full-Length MS Protein Standard

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Product Description


NameGCKR Full-Length MS Protein Standard
Cat#CPFL314230
Protein Nameglucokinase (hexokinase 4) regulator
SymbolGCKR
SynonymsFGQTL5; GKRP
AccessionNM_001486
Cytogenetic2p23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGCKR Full-Length MS Protein Standard (NP_001477), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

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