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OPHN1 Full-Length MS Protein Standard

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Product Description


NameOPHN1 Full-Length MS Protein Standard
Cat#CPFL314215
Protein Nameoligophrenin 1
SymbolOPHN1
SynonymsARHGAP41; MRX60; OPN1
AccessionNM_002547
CytogeneticXq12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionOPHN1 Full-Length MS Protein Standard (NP_002538), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism.

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