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RCBTB1 Full-Length MS Protein Standard

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Product Description


NameRCBTB1 Full-Length MS Protein Standard
Cat#CPFL314169
Protein Nameregulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
SymbolRCBTB1
SynonymsCLLD7; CLLL7; GLP
AccessionNM_018191
Cytogenetic13q14
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionRCBTB1 Full-Length MS Protein Standard (NP_060661), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.

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