ARHGAP26 Full-Length MS Protein Standard


Product Description:

Name ARHGAP26 Full-Length MS Protein Standard
Cat# CPFL313996
Protein NameRho GTPase activating protein 26
SymbolARHGAP26
SynonymsGRAF; GRAF1; OPHN1L; OPHN1L1
AccessionNM_015071
Cytogenetic5q31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW92.1 kDa
Expression TrueORF CloneRC213996
DescriptionARHGAP26 Full-Length MS Protein Standard (NP_055886), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.

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