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NFATC2 Full-Length MS Protein Standard

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Product Description


NameNFATC2 Full-Length MS Protein Standard
Cat#CPFL313966
Protein Namenuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
SymbolNFATC2
SynonymsNFAT1; NFATP
AccessionNM_173091
Cytogenetic20q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNFATC2 Full-Length MS Protein Standard (NP_775114), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

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