Name | CLNK Full-Length MS Protein Standard |
Cat# | CPFL313867 |
Protein Name | cytokine-dependent hematopoietic cell linker |
Symbol | CLNK |
Synonyms | MIST |
Accession | NM_052964 |
Cytogenetic | 4p16.1 |
Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Expression Host | Human HEK293 cells |
Predicted MW | 49.4 kDa |
Expression TrueORF Clone | RC213867 |
Description | CLNK Full-Length MS Protein Standard (NP_443196), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 ) |
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