IFITM5 Full-Length MS Protein Standard


Product Description:

Name IFITM5 Full-Length MS Protein Standard
Cat# CPFL313834
Protein Nameinterferon induced transmembrane protein 5
SymbolIFITM5
SynonymsBRIL; DSPA1; fragilis4; Hrmp1; OI5
AccessionNM_001025295
Cytogenetic11p15.5
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW14.2 kDa
Expression TrueORF CloneRC213834
DescriptionIFITM5 Full-Length MS Protein Standard (NP_001020466), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5 UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195).

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