DIAPH1 Full-Length MS Protein Standard


Product Description:

Name DIAPH1 Full-Length MS Protein Standard
Cat# CPFL313517
Protein Namediaphanous homolog 1 (Drosophila)
SymbolDIAPH1
SynonymsDFNA1; DIA1; DRF1; hDIA1; LFHL1
AccessionNM_001079812
Cytogenetic5q31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW140.1 kDa
Expression TrueORF CloneRC213517
DescriptionDIAPH1 Full-Length MS Protein Standard (NP_001073280), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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