| Name | NEFH Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL313487 |
| Protein Name | neurofilament, heavy polypeptide |
| Symbol | NEFH |
| Synonyms | NFH |
| Accession | NM_021076 |
| Cytogenetic | 22q12.2 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Description | NEFH Full-Length MS Protein Standard (NP_066554), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |
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