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GJA8 Full-Length MS Protein Standard

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Product Description


NameGJA8 Full-Length MS Protein Standard
Cat#CPFL313469
Protein Namegap junction protein, alpha 8, 50kDa
SymbolGJA8
SynonymsCAE; CAE1; CTRCT1; CX50; CZP1; MP70
AccessionNM_005267
Cytogenetic1q21.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGJA8 Full-Length MS Protein Standard (NP_005258), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.

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