ACSL5 Full-Length MS Protein Standard


Product Description:

Name ACSL5 Full-Length MS Protein Standard
Cat# CPFL313380
Protein Nameacyl-CoA synthetase long-chain family member 5
SymbolACSL5
SynonymsACS2; ACS5; FACL5
AccessionNM_203379
Cytogenetic10q25.1-q25.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW75.8 kDa
Expression TrueORF CloneRC213380
DescriptionACSL5 Full-Length MS Protein Standard (NP_976313), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

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