Product Description:

Name	MAPT Full-Length MS Protein Standard
Cat#	CPFL313312
Protein Name	microtubule-associated protein tau
Symbol	MAPT
Synonyms	DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU
Accession	NM_005910
Cytogenetic	17q21.1
Amino Acid Labeled	[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression Host	Human HEK293 cells
Predicted MW	45.7 kDa
Expression TrueORF Clone	RC213312
Description	MAPT Full-Length MS Protein Standard (NP_005901), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

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