HDAC7A Full-Length MS Protein Standard


Product Description:

Name HDAC7A Full-Length MS Protein Standard
Cat# CPFL313214
Protein Namehistone deacetylase 7
SymbolHDAC7A
SynonymsHDAC7, DKFZP586J0917
AccessionNM_016596
Cytogenetic12q13.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW99.5 kDa
Expression TrueORF CloneRC213214
DescriptionHDAC7A Full-Length MS Protein Standard (NP_057680), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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