CD74 Full-Length MS Protein Standard


Product Description:

Name CD74 Full-Length MS Protein Standard
Cat# CPFL312964
Protein NameCD74 molecule, major histocompatibility complex, class II invariant chain
SymbolCD74
SynonymsDHLAG; HLADG; Ia-GAMMA; II
AccessionNM_001025159
Cytogenetic5q32
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW33.3 kDa
Expression TrueORF CloneRC212964
DescriptionCD74 Full-Length MS Protein Standard (NP_001020330), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

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